Breast Cancer Recurrence Risk Calculator

Your details

Choose how you will enter tumour size.
The maximum diameter of the invasive tumour as measured by pathology. Used directly in the NPI formula.
cm
Based on the number of axillary lymph nodes found to contain cancer cells on pathological examination. Score: 1 = no nodes, 2 = 1-3 nodes, 3 = 4 or more nodes.
The Elston-Ellis histological grade (also called Nottingham grade) is based on tubule formation, nuclear pleomorphism, and mitotic count. Your pathology report will state this as Grade 1, 2, or 3.
Whether cancer cells have invaded lymphatic or blood vessels near the primary tumour. LVI is not part of the original NPI formula but is an important independent prognostic factor shown in your results.
NPI ScoreModerate prognosis
3.5

Nottingham Prognostic Index: (0.2 x size cm) + node stage + grade

Prognostic GroupModerate
5-Year Survival1%
10-Year Survival1%
Size component0.5
3.5 NPI
Excellent<2.4Good2.4-3.4Moderate3.4-5.4Poor5.4+

NPI 3.50 - Moderate prognosis group (90% 5-year survival).

  • Your NPI score of 3.50 places you in the Moderate prognostic group.
  • Estimated 5-year survival for this group is approximately 90%, and 10-year survival approximately 77% (all-cause, screened population data).

Next stepThe NPI is one of several tools your oncologist uses alongside receptor status (ER, PR, HER2), genomic assays (e.g. Oncotype DX), age, and overall health to plan your treatment. Always discuss these results with your oncology team.

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