Carboplatin Dose Calculator (AUC / Calvert Formula)

Your details

Used in the Cockcroft-Gault equation (women multiply result by 0.85) and the Devine IBW formula.
Patient age in years. Cockcroft-Gault is validated for adults 18+.
years
Current (actual) body weight.
kg
Patient height, used to calculate ideal body weight (Devine formula).
cm
Serum creatinine in mg/dL. Values below 0.7 mg/dL are floored to 0.7 to avoid GFR overestimation in patients with very low muscle mass.
mg/dL
Area Under the Curve target. Typical ranges: 4-6 for previously treated patients, 5-7 for first-line therapy, up to 7-8 for untreated patients in combination regimens.
mg/mL/min
For obese patients (actual weight > 120% IBW), adjusted body weight reduces GFR overestimation. IBW = 50 kg (men) or 45.5 kg (women) + 2.3 kg per inch above 60 in.
The FDA recommends capping estimated GFR at 125 mL/min when using creatinine-based estimates, because higher values are rarely reliable without measured clearance.
Prior treatment history affects the recommended target AUC range shown in the output.
Carboplatin doseNormal renal function
617mg

Calvert formula result: AUC x (GFR + 25)

Estimated GFR (Cockcroft-Gault)98.4mL/min
GFR used in calculation98.4mL/min
Ideal body weight (IBW)65.9kg
Body weight used for GFR75kg
Max dose at 125 mL/min cap750mg
Recommended AUC rangeTreatment-naive: 5-7 mg/mL/min typical (up to 7-8 in combination)
98.4 mL/min
Kidney failure<15Severe15-30Moderate30-60Mild60-90Normal90+

Estimated carboplatin dose: 617 mg

  • Estimated GFR is 98.4 mL/min (Cockcroft-Gault); 98.4 mL/min is used after the cap.
  • This is an estimated dose for reference only. Clinical protocol, institutional guidelines, and oncology pharmacist verification must be followed before administration.

Next stepVerify against your institution carboplatin protocol; confirm creatinine is stable before dosing.

 = Powered by OnlyCalculators