Fresh Frozen Plasma (FFP) Dose Calculator

Your details

Actual body weight used for dose calculation. Enter in the selected units.
kg
Dose ordered by the prescriber, typically 10-20 mL/kg. Common starting dose is 12-15 mL/kg.
mL/kg
Standard pooled FFP units are typically 200-300 mL. Apheresis-derived plasma units range from 400-600 mL.
Total FFP volumeWithin standard therapeutic dose range
1,050mL

Total volume of FFP to administer

Units to order4.2units
Whole units (rounded up)5units
Estimated factor-level rise15%
Weight used70kg
15 %
Sub-therapeutic<10Standard range10-20High dose20-30Very high dose30+

1050 mL total FFP across 5 units.

  • A dose of 15 mL/kg yields 1050 mL total, requiring 5 standard pooled units of 250 mL each.
  • This dose is expected to raise coagulation factor activity by roughly 15%, based on 1 IU/mL of factor activity in FFP and a standard plasma volume model.
  • Each unit must be ABO-compatible with the recipient. Verify ABO compatibility before issuing units from the blood bank.

Next stepAlways confirm the final order with the responsible clinician or transfusion medicine specialist before administering. This tool assists with arithmetic only.

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