Sum of squares of the three highest AIS region scores (range 0-75)
Highest AIS regionHead and Neck (AIS 3)
2nd highest AIS regionChest (AIS 3)
3rd highest AIS regionAbdomen (AIS 2)
22 ISS
Minor<9Moderate9-16Severe16-25Very Severe / Unsurvivable25+
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ISS is 22 - Severe severity (Major Trauma).
An ISS above 15 meets the standard clinical definition of major trauma (polytrauma). Activation of a trauma team is typically indicated.
The three highest-scoring regions are: Head and Neck (AIS 3), Chest (AIS 3), Abdomen (AIS 2).
The ISS only uses the single worst injury per body region - multiple injuries within the same region are not fully captured by this score.
ISS correlates with mortality, intensive-care length of stay, and hospital stay duration at a population level, but individual patient outcomes depend on many additional factors.
Next stepConsider supplementing ISS with the New Injury Severity Score (NISS), which counts the three worst injuries anywhere regardless of region, and may better reflect polytrauma severity in some patients.