Lidocaine Dose Calculator: Max Safe Dose by Weight

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Enter the patient body weight. For obese patients, lean body weight is recommended by ASRA.
kg
All four are amide-type anesthetics. Each has a different maximum safe dose per kg.
The percentage concentration of the local anesthetic solution (e.g. 1% = 10 mg/mL).
Epinephrine causes vasoconstriction, slowing systemic absorption and allowing a higher maximum dose.
ASRA recommends lean body weight for obese patients to avoid overdose. Enter lean weight manually when using that option.
Maximum doseMaximum safe dose
300mg

Hard ceiling in milligrams; do not exceed

Maximum volume30mL
Dose limit used4.5mg/kg
Concentration10mg/mL
Dose as % of ceiling100%
Absolute ceiling300mg
Weight-based max (mg)300
Absolute ceiling (mg)300

Maximum safe Lidocaine dose: 300 mg (30.0 mL at 1%).

  • The weight-based calculation exceeded the absolute ceiling, so the limit is capped at 300 mg regardless of weight.
  • Without epinephrine the dose ceiling is lower. Adding 1:100,000 or 1:200,000 epinephrine significantly raises the maximum in appropriate tissue.
  • At the chosen 1% concentration (10.00 mg/mL) the maximum volume is 30.0 mL.
  • Local anesthetic systemic toxicity (LAST) can occur below the calculated ceiling, especially with inadvertent intravascular injection. Aspirate before injecting and administer in incremental doses.

Next stepIf LAST is suspected, stop injection immediately, call for help, secure the airway, and prepare 20% lipid emulsion (Intralipid) per ASRA LAST protocol.

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