Lille Score Calculator

Your details

Choose your lab units for bilirubin and creatinine. Albumin uses a separate unit selector.
Patient age in years at the time of admission.
years
Serum albumin at admission. Normal range: 3.5-5.0 g/dL (35-50 g/L).
g/dL
Total serum bilirubin measured at hospital admission, before starting corticosteroid therapy.
mg/dL
Total serum bilirubin measured after 7 days of corticosteroid therapy. A rise or failure to fall significantly indicates non-response.
mg/dL
Serum creatinine. Values above 1.3 mg/dL (115 umol/L) are classified as renal insufficiency and increase the Lille score.
mg/dL
Prothrombin time in seconds at admission. Prolonged PT reflects impaired hepatic synthetic function.
seconds
Lille ScoreResponder (favorable prognosis)
0.177

Score between 0 and 1; cutoff at 0.45 separates responders from non-responders

6-month survival estimate85%
Bilirubin change (day 0 to day 7)3
Renal insufficiencyNo (creatinine <= 1.3 mg/dL)
R (intermediate value)1.5372
0.177
Responder<0.45Non-responder0.45+

Responder: Lille score 0.177 - approximately 85% six-month survival.

  • A Lille score of 0.177 is below the 0.45 cutoff, indicating a response to corticosteroid therapy.
  • Approximately 85% of patients with a score below 0.45 survive to 6 months, suggesting continued steroid therapy is appropriate.
  • Bilirubin decreased by 3.0 mg/dL over 7 days, which is a favorable sign, though the overall score reflects all six variables.

Next stepContinue corticosteroid therapy and monitor liver function tests. Re-evaluate clinically if the patient deteriorates.

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