Lung Nodule Growth Rate and Doubling Time Calculator

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Solid nodules are entirely soft tissue density. Part-solid nodules have a ground-glass component plus a solid core. Pure ground-glass nodules have no solid component.
Use diameter if you have the longest axial dimension from the radiology report. Use volume if your software provided a direct 3D measurement.
Longest diameter on the first (earlier) CT scan, in millimetres.
mm
Longest diameter on the second (later) CT scan, in millimetres.
mm
Number of days between the two CT scans. You can convert months roughly by multiplying by 30.4.
days
Volume Doubling TimeSuspicious
72days

Days for the nodule to double in volume at the observed growth rate (lower = faster growth).

Volume Growth Rate3,212%/year
Specific Growth Rate0.959%/day
Initial volume113.1mm³
Follow-up volume268.1mm³
Volume change137%
BTS risk categorySuspicious for malignancy (VDT < 400 days)
72 days
Suspicious<400Indeterminate400-600Likely benign600+

VDT of 72 days - suspicious for malignancy for a solid nodule.

  • The nodule grew by 137.0% in volume over 90 days.
  • At this rate, the volume would increase by approximately 3212% per year.
  • A VDT below 400 days falls in the range where most malignant lung nodules grow; the British Thoracic Society recommends definitive management (biopsy or resection).

Next stepPrompt multidisciplinary review is recommended. Do not use this calculator as a substitute for expert radiological and clinical assessment.

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