MIPI Calculator (Mantle Cell Lymphoma)

Your details

Patient age in whole years at diagnosis.
years
Eastern Cooperative Oncology Group performance status. ECOG 0-1 contributes 0 to the MIPI score; ECOG 2-4 adds 0.6978.
Serum lactate dehydrogenase level from the laboratory report.
U/L
The upper limit of normal for LDH from your laboratory. Typical ranges are 120-250 U/L depending on the assay. Enter your lab-specific value.
U/L
Total leukocyte count in units of 10⁹ cells per litre (also written as 10³ cells/μL or 10³/mm³). A typical normal range is roughly 4-11 × 10⁹/L. The calculator converts this to cells/μL internally, which is the unit the published MIPI formula uses.
× 10⁹/L
Ki-67 index from immunohistochemistry (percentage of tumor cells positive). Leave at 0 to skip the MIPIb calculation. Values >=30% are associated with markedly inferior survival.
%
MIPI ScoreIntermediate Risk
5.75

Continuous MIPI score (Hoster et al., 2008)

Risk GroupIntermediate
Median Overall Survival~51 months
Simplified MIPI (sMIPI)3
sMIPI Risk GroupLow (0-3)
5.75
Low Risk<5.7Intermediate Risk5.7-6.2High Risk6.2+

MIPI 5.75 - Intermediate Risk

  • The continuous MIPI score of 5.75 places this patient in the intermediate risk group.
  • Median overall survival for the intermediate risk group: ~51 months.
  • The simplified MIPI (sMIPI) point score is 3, consistent with low risk.
  • Enter a Ki-67 value to also calculate the biological MIPI (MIPIb), which refines risk stratification using tumor proliferation.

Next stepIntermediate- and high-risk patients typically receive immunochemotherapy, with or without autologous stem cell transplantation depending on age and comorbidities.

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