Opioid Conversion Calculator (MME)

Your details

The opioid the patient is currently taking.
Total amount taken per day. For transdermal fentanyl or buprenorphine, enter the patch strength in mcg/hr. For all other drugs, enter mg/day.
The opioid you want to convert to. The equianalgesic dose is shown as a starting point before applying a cross-tolerance reduction.
When switching opioids, incomplete cross-tolerance means the equianalgesic dose overestimates the safe starting dose. A 25-50% reduction is standard practice.
Total daily MMELow risk
30MME/day

Morphine milligram equivalents per day for the source opioid

Equianalgesic target dose20
Adjusted starting dose15
Target dose unitmg/day
MME risk levelLow risk
Source dose unitmg/day
30 MME/day
Low risk<50Moderate risk50-90High risk90+

30.0 MME/day - Low risk

  • 30.0 MME/day puts this dose in the "Low risk" category per the 2022 CDC prescribing guideline.
  • Below 50 MME/day is generally the lower-risk range, but there is no completely safe opioid dose. Regular reassessment of benefits and harms is still essential.
  • The equianalgesic dose for Oxycodone (oral) is 20.00 mg/day. After the 25% cross-tolerance reduction, the recommended starting dose is approximately 15.00 mg/day.

Next stepThese values are starting estimates only. Apply clinical judgment, patient-specific factors, and frequent monitoring. Never use this output alone to prescribe.

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